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What is Mitragyna Hirsuta? Uses, Benefits, & History

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Mitragyna Hirsuta: A Popular Kratom Alternative

If you’re looking for kratom alternatives, you really can’t miss Mitragyna hirsuta. What is Mitragyna hirsuta? This tree is in the same genus and family as kratom (Mitragyna speciosa, in the coffee or Rubiaceae family) and the leaf is even known on the street as “kra thum khok.” The leaves are green with light-greenish white veins, and while they are somewhat smaller than kratom leaves, they have a similar structural appearance.

Growing natively in the jungles of Thailand, Vietnam, Cambodia, and Malaysia, Mitragyna hirsuta has become popular in places like Thailand where kratom has been illegal since 1943. It has similar effects to kratom with gentle stimulation at low doses and sedative effects at high doses.

How is Mitragyna Hirsuta Used?

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Traditionally, the leaf is chewed much in the same way as Mitragyna speciosa to help workers maintain their stamina throughout the day. Outside of its original, traditional cultural usage, the plant is sold as a dried powder.

Mitragyna Hirsuta vs Kratom

What is Mitragyna hirsuta’s potency like when compared to kratom? Users of this Southeast Asian herb describe it as being like an “infra-red” strain of kratom with some of the same, if not lessened effects, experienced with red kratom.

Similar to kratom, Mitragyna hirsuta is traditionally used for its calm, energizing effects and to relieve the discomfort of minor aches and pains. Larger doses may also bring on a feeling of sedation. However, this kratom alternative is said to be generally milder and have fewer side effects than Mitragyna speciosa.

What are Mitragyna Hirsuta’s Key Alkaloids

The alkaloids in Mitragyna hirsuta are the active compounds that give the herb its effects. This herb contains an alkaloid called mitraphylline that binds to the same mu-opioid receptors in the brain as mitragynine and is also present in kratom (Mitragyna speciosa) and cat’s claw (Uncaria tomentosa). Another oxindole alkaloid in the herb has been discovered recently that is called isomitraphyllinol, although the effects of this alkaloid are not currently understood and require further study.

Mitraphylline: An Alkaloid with Great Promise

What is Mitragyna hirsuta’s potential for medicinal use? In addition to stimulation and mild pain relief, other potential benefits including a boost in metabolism, a boost for the immune system, and reduced stress have been reported with Mitragyna Hirsuta. However, no studies are readily available to support these supposed benefits.

What is available is research on the effects of the alkaloid mitraphylline when isolated from the cat’s claw herb. In this context, the alkaloid has traditionally been associated with having anti-inflammatory. The mitraphylline in kratom is now being studied for use in these two contexts, and we can hope that Mitragyna hirsuta will be a future candidate for research in the future as well.

What is the Legal Status of Mitragyna Hirsuta?

While kratom and/or its key alkaloids are banned in several states and countries, this kratom substitute is not considered dangerous and is generally legal to sell and possess. However, the FDA has not approved this herb for medicinal use. As a result, the quality of the product sold may vary between vendors. Kratora’s Mitragyna hirsuta is sold for external use only.

Southeast Asian Herbs Brought to You Direct by Kratora

Ensure the highest quality product by purchasing your herb from a reputable vendor such as Kratora. Our dried and crushed mitragyna hirsuta is 100% pure and is sourced from farmers that we have met in person and who use optimal and sustainable growing and harvesting techniques. If you like this kratom alternative, be sure to browse our collections of kratom and other ethnobotanicals for other high-quality plant products.

Shop our Mitragyna hirsuta today to receive same-day shipping on orders submitted before 3 PM EST Monday through Friday and 1 PM EST on Saturdays (excluding holidays).

Please note that none of the products sold on our website are intended to diagnose, treat, cure, or prevent any disease or medical condition.

Please note that the US FDA has not approved this product to be sold for human consumption, sold for external use only. None of the products sold on our website are intended to diagnose, treat, cure, or prevent any disease or medical condition.

Want to learn more about kratom quality and value? Start here:
Why Buying Cheap Kratom Can Be Dangerous

Author Bio


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Colleen is a part owner of Kratora along with her brother David. Kratora was founded in 2013 by David with Colleen joining the team later in 2017. The siblings were born and raised in the Bay Area and spent most of their professional years working in Silicon Valley. Their interest in botanicals began in the early 2000s as they cared for a sick family member and quickly grew into the passion that formed Kratora.

Colleen and the team at Kratora are dedicated to providing the best quality botanicals on the market along with the best customer service. They believe their loyal customers are what makes Kratora so special! Over their many years in business it has always brought them joy to work with their customers and see how botanicals are changing lives for the better.

Kratora’s vision is to help their customers live a better life by consistently providing the highest quality, safest, and purest botanicals on the market. Colleen and her team specialize in regular kratom, kratom extracts, liquid kratom, even kratom gummies — plus a lot of kratom alternative products. Kratora is always looking to expand their product line while remaining true to their high standards.

Colleen believes in transparency between the Kratora team and the expert farmers in South Asia which is why they follow Fair Trade policies. Without these farmers, Kratora would not have any products to sell. As part of Colleen’s commitment in providing the highest quality botanicals, Kratora invests highly into third-party lab testing for all of the products they sell.

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9 thoughts on “What is Mitragyna Hirsuta? Uses, Benefits, & History

    1. Not an expert, but it probably does. The active compounds of herbs can interact with medications and even other herbs. In the case of mitragyna hirsuta, the active compound is mitraphylline, which lowers blood pressure, so it might interact with medications for high blood pressure.

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