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What Are Kratom Alkaloids?

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You’ve probably heard about kratom or even tried out some popular kratom strains such as Maeng Da kratom, Premium Commercial Bali Kratom, White Vein Borneo Kratom, or Thai Red Vein Kratom. The thing is, like many people who are just getting started with this ethnobotanical plant from Southeast Asia, you might not know what’s in the leaves of this plant. Kratom contains various alkaloids that contribute to its effects, including mitragynine and a related compound called 7-Hydroxymitragynine. 

In fact, these two compounds are among the primary reasons why this plant has long been used for traditional medicinal purposes in Southeast Asia. It’s only recently that modern research has identified more than 25 alkaloids in kratom, including these two primary psychoactive compounds. So what are these kratom alkaloids?


Where Do Kratom Alkaloids Come From?

Kratom is a herb that has been grown and used for centuries across Southeast Asia, where people have traditionally chewed on the leaves to combat fatigue or used it as an herbal medicine for various ailments and all different types of physical discomforts. Today, kratom’s popularity is growing because of its mood-lifting, calming, and soothing aromatic effects.

Kratom alkaloids come from the kratom tree’s leaves. These alkaloids vary depending on where the kratom trees grow, the harvesting process and time, and the specific leaf color (green vein, red vein, etc.). Kratom leaves contain at least 25 alkaloids, including Mitragynine, 7-Hydroxymitragynine, Isomitraphyll, and more, which affect different types of neurotransmitters in your brain. The aroma of kratom’s alkaloid content has varying effects from energetic to euphoric sensations to soothing to calming effects.


What are the Most Common Kratom Alkaloids?

Mitragynine and 7-Hydroxymitragynine are mainly responsible for the effects of kratom. Mitragynine is a stimulant alkaloid that works on the mu and kappa opioid receptors. It’s a factor that has long been seen as the reason why so many people have traditionally used kratom as a natural herb in Southeast Asia. While this is not scientifically proven yet, Mitragynine has shown to be a very promising compound in a variety of ways.


On the other hand, 7-Hydroxymitragynine is a sedative alkaloid that acts as both a delta antagonist and μ agonist. This alkaloid is responsible for kratom’s sedative and relaxing effects, which causes users to seek out kratom strains with higher potency. The leaves of the kratom plant contain other varieties of alkaloids, but these two are what give kratom its stimulating and sedating effects.


What are the Effects of Kratom Alkaloids?

Depending on the type of kratom strain, kratom alkaloids can be said to have an uplifting, calming, soothing, relaxing, stimulating, and aphrodisiac aroma or scent. Red vein kratom often has a more calming and soothing effect. White or green kratom strain has a more energetic and euphoric effect. Effects vary greatly depending on the type of kratom strain, potency level, quality of the kratom powder, capsules, or extract.

More research is being done to understand kratom alkaloids and their effects on the body to find out how they can benefit us. There’s a lot of misinformation that needs clarification about kratom alkaloid content, types, what type of strain has more or less of it, and other important factors. Whether you’re new to kratom or a long-time user, it’s important to know the facts about kratom effects and alkaloids. The American Kratom Association notes that educating yourself is the first step to learning more about kratom.


Are Kratom Alkaloids Safe? 

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Kratom is a natural herb that has been used for centuries, originating from different countries in Southeast Asia like Thailand, Malaysia, and Indonesia. In recent years it’s become more popular as an ethnobotanical plant in the West due to its promising medicinal potential that’s still being determined. But the question in many people’s minds is whether or not kratom alkaloid content is safe. 

The FDA doesn’t regulate kratom, so, unfortunately, there’s no way to be 100% sure that the kratom alkaloid content and the safety and quality of kratom products in the market are safe. However, reliable and reputable kratom vendors use third-party lab testing to verify that their products are free of dangerous contaminants and safe for users. Since kratom is a natural plant, it’s important to buy from vendors specializing in selling high-quality herbs with strict quality control standards. 

It’s up to the manufacturers of different kratom product strains or extracts to determine how potent they are and label their products with accurate information. Buyers must also be aware of the possibility that kratom alkaloid content may vary from one batch to another. This makes it crucial for users to do more research, read reviews, and consult with experts before determining the kratom product best suited for their needs. 


Shop Fresh, Organic Kratom Products at Kratora



Now that you know what kratom alkaloids are, you might be interested in trying our kratom for the first time or even adding new products to your existing kratom collection. At Kratora, our kratom is always fresh and sourced from the best growers since 2013. Shop organic, all-natural, and fresh kratom products at our online store and enjoy our 30-day money-back guarantee, fast same-day priority shipping, and free shipping +$75. 

Have any questions about kratom alkaloid content? Contact us.

Want to learn more about kratom quality and value? Start here:
Why Buying Cheap Kratom Can Be Dangerous

Author Bio


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Colleen is a part owner of Kratora along with her brother David. Kratora was founded in 2013 by David with Colleen joining the team later in 2017. The siblings were born and raised in the Bay Area and spent most of their professional years working in Silicon Valley. Their interest in botanicals began in the early 2000s as they cared for a sick family member and quickly grew into the passion that formed Kratora.

Colleen and the team at Kratora are dedicated to providing the best quality botanicals on the market along with the best customer service. They believe their loyal customers are what makes Kratora so special! Over their many years in business it has always brought them joy to work with their customers and see how botanicals are changing lives for the better.

Kratora’s vision is to help their customers live a better life by consistently providing the highest quality, safest, and purest botanicals on the market. Colleen and her team specialize in regular kratom, kratom extracts, liquid kratom, even kratom gummies — plus a lot of kratom alternative products. Kratora is always looking to expand their product line while remaining true to their high standards.

Colleen believes in transparency between the Kratora team and the expert farmers in South Asia which is why they follow Fair Trade policies. Without these farmers, Kratora would not have any products to sell. As part of Colleen’s commitment in providing the highest quality botanicals, Kratora invests highly into third-party lab testing for all of the products they sell.

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One thought on “What Are Kratom Alkaloids?

  1. After many years and a multiple vendors….I can honestly say that Kratora deals only in ABOVE GRADE plant ethnobotanicals. They go above and beyond one’s expectations—EVERY SELECTION seems to be far superior than the last. An don’t forget they sell MANY kratom alternatives which are worth investigating!!!?

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